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TU Berlin

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Prof. Dr. Thomas Friedrich

Research of the group is focussed on the relationships between structure and function, dynamics and regulation of ion-translocating membrane proteins such as active ion pumps or ion channels. Since we are interested in understanding these functional properties in a native biological membrane environment we express the proteins in eukaryotic cells. Based on molecular biological techniques we predominantly perform electrophysiological experiments (two-electrode voltage-clamping on oocytes or patch-clamp on oocyte membrane patches or on transfected cells) and combine these with fluorimetric techniques in order to reveal dynamic processes during protein function.

Physical Chemistry / Molecular Material Sciences

Prof. Dr. Michael Gradzielski 

Central to the research of the work group is the investigation of colloidal system, especially with respect to correlations between microscopic structure and dynamic and the macroscopic properties. The general aim is the understanding of the properties of these complex mesoscopic system based on their molecular composition. Experimental techniques used for this purpose are scattering methods (SLS, DLS, SAXS, SANS), stopped-flow technique, UV-vis, IR, fluorescence spectroscopy, AFM, surface and interfacial tension, rheology, DSC (differential scanning calorimetry). 

Physical Chemistry / Biophysical Chemistry

Prof. Dr. Peter Hildebrandt

Research activities focus on the investigation of elementary chemical processes of complex biological and chemical systems, in particular, electron transfer, interfacial processes, and photoinduced reactions. These fundamental topics constitute the linkage between the various research projects that also cover methodical aspects. We are predominantly employing stationary and time-resolved vibrational spectroscopic techniques that are well established in our group. Further experimental approaches include other spectroscopic (e. g. UV-vis absorption, circular dichroism, electron paramagnetic resonance), electrochemical and microscopic techniques as well as biochemical methods that are, in part, employed in collaboration with other research groups inside and outside the Max-Volmer Laboratory. The experimental studies are complemented by theoretical methods.

Applied Physical Chemistry

Chair in replacement

untill 2016: Prof. Dr. Regine von Klitzing (moved to TU Darmstadt)


Quantum Chemistry

Prof. Dr. Martin Kaupp

Since the move of Prof. Dr. Martin Kaupp from Würzburg to Berlin in 2010, quantum chemistry is again centrally represented at Institut für Chemie at Technische Universität Berlin. The group works on a wide spectrum of projects from the development of methods and algorithms of modern density functional theory to applications that range from bioinorganic, inorganic and organometallic chemistry to organic materials and bioradicals. The computation of spectroscopic parameters of NMR and EPR as well as the consideration of relativistic effects (e.g. of spin-orbit coupling) play important roles. This allows numerous applications across the entire periodic table, e.g. also in catalysis within the framework of the unicat excellence cluster. Beyond accurate and efficient calculations, qualitative interpretations of the observations and the development of novel models are generally at the center of interest.

Modeling of biomolecular systems

Theoretical Chemistry

Prof. Dr. Martin Schoen

The focus of research in our group is on soft condensed matter systems. Employing methods and techniques of modern statistical physics (e.g. computer simulations of classical many-particle systems, density functional theory) we investigate both static and dynamic properties of thermal fluidic systems. We are concerned with the interplay between intermolecular interactions and the thermal energy stored in these systems. A focal point in this more general context are nanostructured systems. The emphysis here is on wetting and adsorption phenomena in confinement and at nanostructured solid surfaces from which a better understanding of transport and catalytic processes controlled by such functional materials will emerge. A second focus is on supramolecular fluids which are investigated by means of coarse-graining techniques in mesoscale computer simulations.

Structural Chemical Biology – Cheminformatics

Prof. Dr. Han Sun 

Prof. Han Sun is a professor at the Institute for Chemistry at TU Berlin and a research group leader at the Leibniz Research Institute for Molecular Pharmacology. In her research she focuses on molecular modeling and molecular dynamics as well as on other chem- and bioinformatic methods for the development of new bioactive molecules and the investigation of their interactions with biological target structures. In addition, she develops new NMR methods for the structure elucidation of complex natural products and pharmacologically active substances.

Supernumerary professors

Apl. Prof. Dr. C. Aris Dreismann

Junior research groups

Dr. Oliver Lenz

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